Leonard Hofstadter

experimental physicist

works in Caltech

Although Leonard feels at home with his geek colleagues, he wants to be more social. Among the main characters, he generally has the least amount of difficulty interacting with ”non-geek” individuals.

Sheldon Cooper

theoretical physicist

Works in Caltech

Sheldon is logical and has an overly extensive general knowledge. He possesses an eidetic memory and an IQ of 187

Penny

waitress

Works in local Cheesecake Factory

Penny has an aspirations of becoming an actress. She is not particularly intellectually gifted or savvy in a specific technical field, but she has great social skills and is very knowledgeable about pop culture.

Howard Wolowitz

an aerospace engineer

Works in Caltech’s Department of Applied Physics

He has shown limited success with other women. Eventually, he found his girlfriend, Bernadette , An amateur microbiologist.

Rajesh Koothrappali

astrophysicist

Works in Caltech

He is very shy around women and is physically unable to talk to them unless he drinks alcohol. However, he has had much better luck with women as opposed to his overly confident best friend Howard.